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In the second quarter of Thursday’s loss against the Tennessee Titans, Jimmy Garoppolo suffered a thumb sprain on his throwing hand, affecting his performance in the remainder of the contest.

The injury could also affect his availability as the 49ers look to bounce back in Week 17 as they host the Houston Texans. On Monday, the team returned to the SAP Performance Facility and Garoppolo was absent from the team’s first practice.

Garoppolo’s absence gave third-overall pick Trey Lance first team reps during Monday’s session, with the opportunity to see more playing time should the starting quarterback miss multiple practices.