49ers Must-Starts for Fantasy Championship Week

Deebo Samuel became the first player in NFL history with 1,200 receiving yards and 300 rushing yards in the same season and is a top-10 WR this week. Brandon Aiyuk and George Kittle also remain fantasy must-starts no matter who is under center for San Francisco. Both have been producing with Garoppolo, while Lance’s bigger arm should theoretically help Aiyuk downfield, and the rookie QB frequently targeted his college tight ends in the red zone.

Rex Burkhead was surprisingly the No. 3 fantasy back last week, but he’s best left on benches Sunday against the No. 2 ranked San Francisco run defense in DVOA. However, rookie Davis Mills has been playing well lately, getting 7.5 YPA with a 5:1 TD:INT ratio over the last three games that have all come against top-15 pass defenses. Mills gets Brandin Cooks back this week and faces a 49ers pass-funnel defense that’s been hit hard by injuries to their secondary. Mills is a superflex option, while Cooks is a top-20 WR.